PD 174265

CAS No. 216163-53-0

PD 174265 ( PD174265; PD-174265; N-{4-[(3-Bromophenyl)amino]quinazolin-6-Yl}propanamide )

Catalog No. M27910 CAS No. 216163-53-0

PD 174265 is an effective, selective and reversible inhibitor of epidermal growth factor receptor (EGFR) with an IC50 of 0.45 nM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 45 Get Quote
10MG 58 Get Quote
25MG 86 Get Quote
50MG 121 Get Quote
100MG 175 Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    PD 174265
  • Note
    Research use only, not for human use.
  • Brief Description
    PD 174265 is an effective, selective and reversible inhibitor of epidermal growth factor receptor (EGFR) with an IC50 of 0.45 nM.
  • Description
    PD 174265 is an effective, selective and reversible inhibitor of epidermal growth factor receptor (EGFR) with an IC50 of 0.45 nM.
  • Synonyms
    PD174265; PD-174265; N-{4-[(3-Bromophenyl)amino]quinazolin-6-Yl}propanamide
  • Pathway
    Angiogenesis
  • Target
    EGFR
  • Recptor
    Influenza Virus
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    216163-53-0
  • Formula Weight
    371.2
  • Molecular Formula
    C17H15BrN4O
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    CCC(=O)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Takizawa N, et al. Anti-influenza virus activity of a salcomine derivative mediated by inhibition of viral RNA synthesis. Arch Virol. 2018 Jun;163(6):1607-1614.
molnova catalog
related products
  • CHF5074

    CHF5074, a γ-secretase modulator, reduces Aβ42/40 secretion (IC50: 3.6/18.4 μM).

  • EGFR/ErbB2 Inhibitor

    EGFR/ErbB2 Inhibitor is a cell-permeable inhibitor of EGFR and c-ErbB2 (IC50s = 20 and 79 nM, respectively)

  • Sanguinarine chlorid...

    Sanguinarine-containing mouthwashes are marketed as anti-plaque and anti-malodor.